Butox^® 7.5 pour on

Butox^® 7.5 is a ready to use pour on for the long term control of external parasites on cattle and sheep.

Composition

Active substance: Deltamethrin 0.750 g/100 mL
Excipients: Formaldehyde solution (35%) and Propylene glycol

Indications for use

Butox^® is effective against tick, lice, fly and ked infestations and has shown to be effective against biting Culicoides midges.

Method of administration

Pour on the product along the backline of the animals from the head to the tail. See table for recommended dose rates.

Dose rate of Butox^® 7.5 pour on for cattle and sheep
Indications	Dose Rate
Flies Prevention and treatment of biting and nuisance flies on calves and other cattle	Cattle
	up to 100kg	10ml
	100kg to 300kg	20ml
	more than 300kg	30ml
Lice Prevention and treatment of biting and sucking lice on calves, adult cattle and sheep	Cattle and sheep
	Up to 500kg	10ml
	More than 500kg	20ml
Keds Prevention and treatment of sheep keds	Sheep 10ml per animal
Ticks Prevention and treatment ticks	Cattle 15ml per 100kg Not more than 75 ml per animal

Flies: a single application provides protection against flies for 8 to 10 weeks depending on the infestation degree, fly species and weather conditions. Treatment should he repeated within 8 to 10 weeks depending on the weather and the fly species.

Lice: a single application is usually sufficient. All in contact animals must he treated at the same time. Sheep should be treated after shearing.

Ticks: a single application provides protection against ticks for 4-5 weeks.

Mechanism of action

After dermal application, deltamethrin is slightly absorbed through skin of cattle and sheep and remains available to the target ectoparasite. The main route of excretion of the absorbed amount in the target animal is the faeces. In terms of residues, fat is the target issue.

Deltamethrin affects neurotransmission in the target parasite. Upon absorption deltamethrin initially stimulates the nervous system leading to hyperexcitement with tremors and spasms. After the excitement phase the action of nerve cells becomes inhibited leading to paralysis and death of the parasite.

Precautions and warnings

Adverse reactions
None observed.

Use during pregnancy and lactation
Can be used during pregnancy and lactation.

Interaction with other veterinary medicinal products and other forms of interaction
Some organo-phosphorous insecticides can reduce metabolism rate and thus enhance deltamethrin toxicity. Therefore, it is not advisable to proceed with such combinations.

Special precautions for use, including special precautions to be taken by the person administering the veterinary medicinal product to animals
Do not eat, drink or smoke while using the product.
Wash hands and exposed skin before meals and after work.

Special precautions for the disposal of unused veterinary medicinal product or waste materials
Any unused product or waste material should be disposed of in accordance with the national requirements. Dangerous to aquatic life. Do not contaminate ponds, waterways or ditches with the product or used containers.

Contraindications
None

Special warnings for each target species
None